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Anti-CD22 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CD22 Antibody MOM-18198 1mg Please Inquiry
Product Detail
Cat
MOM-18198
Product Overview
Recombinant Humanized (from mouse) Antibody binds selectively to Human CD22, expressed in Chinese Hamster Ovary cells(CHO)
Target
CD22
Type
Humanized (from mouse) IgG4 - kappa
Immunogen
Human tonsil lymphocytes
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut, ELISA and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G4, anti-(human CD22 (antigen)) (human-mouse monoclonal G544 heavy chain), disulfide with human-mouse monoclonal G544 Kappa-chain, dime
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
CD22 or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases.CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signalling.
Function
protein binding; sugar binding;
Gene ID
933
Synonyms
CD22; CD22 molecule; CD22 antigen; B-cell receptor CD22; sialic acid binding Ig like lectin 2; SIGLEC 2; SIGLEC2; BL-CAM; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; SIGLEC-2; FLJ22814; MGC130020;
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