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Anti-CD33 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CD33 Antibody Fab Fragment MOM-18013-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18013-F(E)
Product Overview
Recombinant Humanized (from mouse) Antibody Fab Fragment binds selectively to Human CD33, expressed in Chinese Hamster Ovary cells(CHO)
Target
CD33
Type
Fab Fragment based on Humanized (from mouse) IgG4 kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by analysis by SDS-PAGE.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Function
receptor activity; sugar binding;
Gene ID
945
Synonyms
CD33; CD33 molecule; CD33 antigen (gp67); myeloid cell surface antigen CD33; FLJ00391; p67; sialic acid binding Ig like lectin 3; SIGLEC 3; SIGLEC3; gp67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC-3;
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