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Anti-CD3E Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CD3E Antibody MOM-18245 1mg Please Inquiry
Product Detail
Cat
MOM-18245
Product Overview
Recombinant Human Antibody is specific to Human CD3 epsilon, expressed in Chinese Hamster Ovary cells(CHO)
Target
CD3 epsilon
Type
Human IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, IP, FC, FuncS, Neut, IF and most other immunological methods.
Protein Construction
Immunoglobulin G1-kappa, anti-[Homo sapiens CD3E (CD3epsilon)], Homo sapiens monoclonal antibody;gamma1 heavy chain (1-448) [Homo sapiens VH (IGHV3-33*01(95.90%) -(IGHD)-IGHJ2*01) [8.8.11] (1-118) -IGHG1*03 CH2L1.3>A, L1.2>E (119-448)], (221-215")-disulfi
Predicted N terminal
H chain: QVQLVES; L Chain: EIVLTQS
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Function
SH3 domain binding; T cell receptor binding; protein heterodimerization activity; protein kinase binding; receptor activity; receptor signaling complex scaffold activity; receptor signaling protein activity; transmembrane signaling receptor activity;
Gene ID
916
Synonyms
CD3E; CD3e molecule, epsilon (CD3-TCR complex); CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell antigen receptor complex, epsilon subunit of T3; T3E; TCRE; FLJ18683;
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