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Anti-CD40LG Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CD40LG Antibody Fab Fragment MOM-18027-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18027-F(P)
Product Overview
Recombinant Humanized (from mouse) Antibody Fab Fragment specifically binds to Human CD40L, expressed in E. coli
Target
CD40L
Type
Fab Fragment based on Humanized (from mouse) IgG1 - kappa
Immunogen
Animals were immunized with D1.1 cells.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
At -20°C for one year.
Background
Antigen Description
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
Function
CD40 receptor binding; cytokine activity; tumor necrosis factor receptor binding;
Gene ID
959
Keywords
0
Synonyms
CD40LG; CD40 ligand; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; tumor necrosis factor (ligand) superfamily member 5; CD40-L; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; IGM; IMD3; HIGM1; T-BAM; TNFSF5;
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