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Anti-CD6 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CD6 Antibody MOM-18247 1mg Please Inquiry
Product Detail
Cat
MOM-18247
Product Overview
Recombinant Humanized (from mouse) Antibody is against Human CD6, expressed in Chinese Hamster Ovary cells(CHO)
Target
CD6
Type
Humanized (from mouse) IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, WB and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1-kappa, anti-[Homo sapiens CD6 (Tp120, T12)], humanized monoclonal antibody; gamma1 heavy chain (1-449) [humanized VH (Homo sapiensIGHV3-21*08 (83.70%) -(IGHD)-IGHJ5*01) [8.8.12] (1-119) -Homosapiens IGHG1*01 (120-449)], (222-214")-disulfid
Predicted N terminal
H chain: EVQLVES; L Chain: DIQMTQS
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
Function
scavenger receptor activity;
Gene ID
923
Synonyms
CD6; CD6 molecule; CD6 antigen; T-cell differentiation antigen CD6; Tp120; T12; TP120; FLJ44171;
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