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Recombinant Anti-CEA MAb Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CEA Antibody Fab Fragment MOM-H03-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-H03-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment is directed against Human CEA, expressed in HEK293
Target
CEA
Type
Mouse Fab-IgG
Species Reactivity
Human
Expression Host
HEK293
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Purity
Purity >95% by SDS-PAGE.
Purification
Purified by Nickel ion affinity chromatography
Storage
At -20°C for one year.
Background
Introduction
Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
Keywords
CEACAM1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); BGP; BGP1; BGPI; antigen CD66; CD66a antigen; CEACAM3; carcinoembryonic antigen-related cell adhesion molecule 3; CEA; CGM1; Carcinoembryonic antigen
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