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Anti-CEACAM1 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CEACAM1 Antibody Fab Fragment MOM-18014-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18014-F(P)
Product Overview
Recombinant Mouse Antibody Fab Fragment binds selectively to Human CEA, expressed in E. coli
Target
CEA
Type
Fab Fragment based on Mouse Fab' - G1
Immunogen
Full length native protein (CEA).
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1, anti-(human carcinoembryonic antigen) Fab' fragment (mouse monoclonal gamma 1-chain), disulfide with mouse monoclonal light chain
Purity
Purity >95% by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced in gastrointestinal tissue during fetal development, but the production of CEA stops before birth. Therefore, it is usually present only at very low levels in the blood of healthy adults. However, the serum levels are raised in some types of cancer, which means that it can be used as a tumor marker in clinical tests. Serum levels can also be elevated in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI) cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
Function
molecular_function; protein binding;
Gene ID
634
Synonyms
CEACAM1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); BGP; carcinoembryonic antigen-related cell adhesion molecule 1; BGP1; CD66a; antigen CD66; CD66a antigen; BGPI;
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