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Anti-FLT1 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human FLT1 Antibody Fab Fragment MOM-18177-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18177-F(E)
Product Overview
Recombinant Human Antibody Fab Fragment is directed against Human VEGFR-1, expressed in Chinese Hamster Ovary cells(CHO)
Target
VEGFR-1
Type
Fab Fragment based on Human IgG1 - kappa
Immunogen
Recombinant human soluble extracellular Flt-1 Ig-like loop 1 to 5 (sFlt-1(D5)).
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Predicted N terminal
H chain: QAQVVES; L Chain: EIVLTQS
Purity
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
At -20°C for one year.
Background
Antigen Description
Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
Function
ATP binding; growth factor binding; nucleotide binding; protein binding; receptor activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor-activated receptor activity; vascular endothelial growth factor-activated receptor activity;
Gene ID
2321
Synonyms
FLT1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FLT; vascular endothelial growth factor receptor 1; VEGFR1; FLT-1; VEGFR-1; fms-like tyrosine kinase 1; tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; vascular permeability factor receptor;
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