|Recombinant Anti-Human FOLH1 Antibody
- Product Overview
- Recombinant Mouse Antibody is bind to Human PMSA, expressed in Chinese Hamster Ovary cells(CHO)
- Mouse IgG1 - kappa
- The details of the immunogen for this antibody are not available.
- Species Reactivity
- Expression Host
- Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, WB and most other immunological methods.
- Tested positive against native antigen.
- Protein Construction
- Immunoglobulin G1, anti-(human prostatic carcinoma cell) (mouse monoclonal 7E11-C5.3 gamma 1-chain), disulfide with mousemonoclonal 7E11-C5.3 light chain, dimer
- >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
- Antigen Description
- Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
- carboxypeptidase activity; dipeptidase activity; metal ion binding; metallopeptidase activity; peptidase activity;
- Gene ID
- FOLH1; folate hydrolase (prostate-specific membrane antigen) 1; FOLH; glutamate carboxypeptidase 2; GCP2; GCPII; glutamate carboxylase II; glutamate carboxypeptidase II; NAALAD1; NAALAdase; PSM; PSMA; NAALADase I; membrane glutamate carboxypeptidase; cell growth-inhibiting gene 27 protein; folylpoly-gamma-glutamate carboxypeptidase; prostate specific membrane antigen variant F; pteroylpoly-gamma-glutamate carboxypeptidase; N-acetylated alpha-linked acidic dipeptidase 1; N-acetylated-alpha-linked acidic dipeptidase I; FGCP; mGCP;
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