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Anti-FOLR1 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human FOLR1 Antibody Fab Fragment MOM-18113-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18113-F(E)
Product Overview
Recombinant Humanized (from mouse) Antibody Fab Fragment specifically binds to Human folate receptor 1, expressed in Chinese Hamster Ovary cells(CHO)
Target
folate receptor 1
Type
Fab Fragment based on Humanized (from mouse) IgG1 - kappa
Immunogen
Gestational choriocarcinoma cell line, Lu-75.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H chain: EVQLVES; L Chain: DIQLTQS
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
Function
folic acid binding; receptor activity;
Gene ID
2348
Synonyms
FOLR1; folate receptor 1 (adult); FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18; FBP;
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