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Anti-FOLR1 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human FOLR1 Antibody MOM-18113 1mg Please Inquiry
Product Detail
Cat
MOM-18113
Product Overview
Recombinant Humanized (from mouse) Antibody binds selectively to Human folate receptor 1, expressed in Chinese Hamster Ovary cells(CHO)
Target
folate receptor 1
Type
Humanized (from mouse) IgG1 - kappa
Immunogen
Gestational choriocarcinoma cell line, Lu-75.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1-kappa, anti-[Homo sapiens folate receptor 1 (FOLR1, folate receptor alpha, FR-alpha, adult folate-binding protein, FBP, ovarian tumor-associated antigen MOv18)], humanized monoclonal antibody
Predicted N terminal
H chain: EVQLVES; L Chain: DIQLTQS
Purity
>95.0% as determined by analysis by RP-HPLC.
Storage
At -20°C for one year.
Background
Antigen Description
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
Function
folic acid binding; receptor activity;
Gene ID
2348
Synonyms
FOLR1; folate receptor 1 (adult); FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18; FBP;
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