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Anti-GD3 ganglioside Antibody scFv

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human GD3 ganglioside Antibody scFv Fragment MOM-18131-S(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18131-S(P)
Product Overview
Recombinant Chimeric (mouse/human) Antibody scFv Fragment specifically binds to Human GD3 ganglioside, expressed in E. coli
Target
GD3 ganglioside
Type
scFv Fragment from Chimeric (mouse/human) IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Introduction
This is a chimeric monoclonal antibody being developed for the treatment of malignant melanoma.
Antigen Description
Almost all melanomas, astrocytomas, a proportion of sarcomas, a small number of carcinomas, some nevi, as well as normal melanocytes express GD3 antigen. It is one of the most important markers for malignant melanoma. Antibodies to the GD3 ganglioside can induce partial remission of tumor growth in animals as well as in Humans via enhancement of cytotoxic and proliferative response of lymphocytes.
Keywords
GD3 ganglioside
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