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Anti-ICAM1 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ICAM1 Antibody Fab Fragment MOM-18241-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18241-F(P)
Product Overview
Recombinant Mouse Antibody Fab Fragment binds selectively to Human ICAM-1, expressed in E. coli
Target
ICAM-1
Type
Fab Fragment based on Mouse Fab' - G2a
Immunogen
Tissue / cell preparation (Human). (Burkitt's lymphoma cell line RAJI).
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Function
cell surface binding; integrin binding; protein binding; receptor activity; transmembrane signaling receptor activity;
Gene ID
3383
Synonyms
ICAM1; intercellular adhesion molecule 1; BB2; CD54; human rhinovirus receptor; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; P3.58;
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