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Anti-ICAM1 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ICAM1 Antibody MOM-18241 1mg Please Inquiry
Product Detail
Cat
MOM-18241
Product Overview
Recombinant Mouse Antibody is against Human ICAM-1, expressed in Chinese Hamster Ovary cells(CHO)
Target
ICAM-1
Type
Mouse Fab' - G2a
Immunogen
Tissue / cell preparation (Human). (Burkitt's lymphoma cell line RAJI).
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G 2a (human monoclonal BI-RR-1 anti-human antigen CD 54), disulfide with mouse monoclonal BI-RR-1 light chain, dimer, reaction product with alpha-(2-carboxyethyl)-ω-methoxypoly(oxy-1,2-ethanediyl)
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
At -20°C for one year.
Background
Antigen Description
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Function
cell surface binding; integrin binding; protein binding; receptor activity; transmembrane signaling receptor activity;
Gene ID
3383
Synonyms
ICAM1; intercellular adhesion molecule 1; BB2; CD54; human rhinovirus receptor; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; P3.58;
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