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Anti-ITGA2 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGA2 Antibody MOM-18251 1mg Please Inquiry
Product Detail
Cat
MOM-18251
Product Overview
Recombinant Humanized Antibody is against Human ITGA2, expressed in Chinese Hamster Ovary cells(CHO)
Target
ITGA2
Type
Humanized IgG4 - kappa
Immunogen
Whole human keratinocytes.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, Neut, ELISA and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G4-kappa, anti-[Homo sapiens ITGA2 (integrin alpha 2, CD49b, GPIa, subunit of the alpha2beta1 integrin (VLA-2, collagen receptor))], humanized monoclonal antibody
Predicted N terminal
H chain: QVQLQES; L Chain: DIVMTQS
Purity
>95.0% as determined by analysis by SDS-PAGE.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Function
collagen binding; protein binding; receptor activity;
Gene ID
3673
Synonyms
ITGA2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); CD49B; integrin alpha-2; CD49b; integrin alpha 2; collagen receptor; VLA-2 subunit alpha; platelet antigen Br; platelet glycoprotein Ia; platelet glycoprotein GPIa; CD49 antigen-like family member B; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; BR; GPIa; VLA-2; VLAA2; BDPLT9;
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