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Recombinant Anti-ITGA4+ITGB7 MAb Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGA4+ITGB7 Antibody Fab Fragment MOM-H02-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-H02-F(P)
Product Overview
Recombinant human Antibody Fab Fragment specifically binds to Human ITGA4+ITGB7, expressed in E. coli
Target
ITGA4+ITGB7
Type
human Fab-IgG2 - kappa
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
ITGA4_ITGB7(integrin alpha4 (CD49d)_beta7, integrin alpha4_beta7, integrin α4β7, lymphocyte Peyer s patch adhesion molecule 1, LPAM-1) [Homo sapiens]
Cellular Localization
kappa
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Purification
Purified by Nickel ion affinity chromatography
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Introduction
Integrins are transmembrane receptors that are the bridges for cell-cell and cell-extracellular matrix (ECM) interactions. When triggered, integrins in turn trigger chemical pathways to the interior (signal transduction), such as the chemical composition and mechanical status of the ECM, which results in a response (activation of transcription) such as regulation of the cell cycle, cell shape, and/or motility; or new receptors being added to the cell membrane
Keywords
ITGA4; ITGB7; Integrin α4β7; CD49d/β7
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