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Anti-ITGAV Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGAV Antibody MOM-18076 1mg Please Inquiry
Product Detail
Cat
MOM-18076
Product Overview
Recombinant Human Antibody is bind to Human CD51, expressed in Chinese Hamster Ovary cells(CHO)
Target
CD51
Type
Human IgG1 - kappa
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut, ELISA and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1, anti-(human integrin alpha-V (vitronectin receptor subunit alpha or CD51); human monoclonal CNTO 95 γ1 heavy chain (222-215")-disulfide with human monoclonal CNTO 95 kappa light chain dimer (228-228"":231-231"")-bisdisulfide
Predicted N terminal
H Chain: QVQLVES; L Chain: EIVLTQS
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi"s sarcoma lesions.
Function
contributes_to insulin-like growth factor I binding; contributes_to opsonin binding; protein binding; protein kinase C alpha binding; contributes_to protein kinase C binding; receptor activity; transforming growth factor beta binding;
Gene ID
3685
Synonyms
ITGAV; integrin, alpha V; antigen identified by monoclonal L230 , integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , MSK8, vitronectin receptor , VNRA, VTNR; integrin alpha-V; CD51; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); MSK8; VNRA; VTNR; DKFZp686A08142;
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