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Anti-ITGAV+ITGB3 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGAV+ITGB3 Antibody MOM-18025 1mg Please Inquiry
Product Detail
Cat
MOM-18025
Product Overview
Recombinant Humanized (from mouse) Antibody is directed against Human CD51+CD61, expressed in Chinese Hamster Ovary cells(CHO)
Target
CD51+CD61
Type
Humanized (from mouse) IgG1
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H Chain: QVQLVES; L Chain: EIVLTES
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. They are known to participate in cell adhesion as well as cell-surface mediated signalling. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. CD51 encodes integrin alpha chain V. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Alpha-V integrins have been implicated in many developmental processes and are therapeutic targets for inhibition of angiogenesis and osteoporosis.
Keywords
ITGAV; integrin, alpha V; antigen identified by monoclonal L230, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), MSK8, vitronectin receptor , VNRA, VTNR; integrin alpha-V; CD51; integrin alphaVbeta3; vitronectin receptor subunit
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