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Anti-ITGB2 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGB2 Antibody Fab Fragment MOM-18154-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18154-F(E)
Product Overview
Recombinant Humanized (from mouse) Antibody Fab Fragment specifically binds to Human CD18, expressed in Chinese Hamster Ovary cells(CHO)
Target
CD18
Type
Fab Fragment based on Humanized (from mouse) IgG1
Immunogen
Tissue / cell preparation (Human). (Leucocytes of a patient suffering from a LGL-type leukaemia).
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1, anti-[human integrin beta2] F[ab"]2 fragment [human-mouse monoclonal γ1-chain], disulfide with human-mouse monoclonal light chain, dimeralpha
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.
Function
binding; glycoprotein binding; protein kinase binding; receptor activity;
Gene ID
3689
Synonyms
ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); CD18, integrin, beta 2 (antigen CD18 (p95), lymphocyte function associated antigen 1; macrophage antigen 1 (mac 1) beta subunit) , MFI7; integrin beta-2; LFA 1; MAC 1; integrin beta chain, beta 2; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor); LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1;
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