|Recombinant Anti-Human ITGB2 Antibody
- Product Overview
- Recombinant Humanized (from mouse) Antibody is directed against Human ITGB2, expressed in Chinese Hamster Ovary cells(CHO)
- Humanized (from mouse) IgG4
- The details of the immunogen for this antibody are not available.
- Species Reactivity
- Expression Host
- Suitable for use in FuncS, IF, Neut, ELISA and most other immunological methods.
- Tested positive against native antigen.
- Protein Construction
- ImmunoglobulinG4, anti-(human CD11 (antigen)/integrin b2) (human-mousemonoclonal Hu23F2G g4-chain), disulfide with human-mouse monoclonal Hu23F2G k-chain, dimer
- Predicted N terminal
- H chain: QVQLVQS; L Chain: DIQMTQS
- >95.0% as determined by analysis by SDS-PAGE.
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
- Antigen Description
- Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.
- binding; glycoprotein binding; protein kinase binding; receptor activity;
- Gene ID
- ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); CD18, integrin, beta 2 (antigen CD18 (p95), lymphocyte function associated antigen 1; macrophage antigen 1 (mac 1) beta subunit) , MFI7; integrin beta-2; LFA 1; MAC 1; integrin beta chain, beta 2; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor); LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1;
- Download Datasheet:
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