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Anti-ITGB3 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGB3 Antibody Fab Fragment MOM-18109-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18109-F(E)
Product Overview
Recombinant Humanized (from mouse) Antibody Fab Fragment specifically binds to Human Integrin lpha 2b beta 3, expressed in Chinese Hamster Ovary cells(CHO)
Target
Integrin lpha 2b beta 3
Type
Fab Fragment based on Humanized (from mouse) Fab - G1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1, anti- (human integrin alpha IIb beta3) Fab fragment (human-mouse monoclonal C4G1 γ1-chain), disulfide with human-mouse monoclonal C4G1 kappa-chain.
Predicted N terminal
H chain: QVQLVQS; L Chain: DIQMTQT
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Antigen Description
The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
Function
cell adhesion molecule binding; identical protein binding; integrin binding; platelet-derived growth factor receptor binding; protein binding; protein disulfide isomerase activity; receptor activity; vascular endothelial growth factor receptor 2 binding; vascular endothelial growth factor receptor 2 binding;
Gene ID
3690
Synonyms
ITGB3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); GP3A; integrin beta-3; CD61; GPIIIa; platelet glycoprotein IIIa; platelet membrane glycoprotein IIIa; GT; BDPLT2;
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