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Anti-ITGB3 Antibody scFv

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGB3 Antibody scFv Fragment MOM-18109-S(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18109-S(P)
Product Overview
Recombinant Humanized (from mouse) Antibody scFv Fragment is directed against Human Integrin lpha 2b beta 3, expressed in E. coli
Target
Integrin lpha 2b beta 3
Type
scFv Fragment from Humanized (from mouse) Fab - G1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
Function
cell adhesion molecule binding; identical protein binding; integrin binding; platelet-derived growth factor receptor binding; protein binding; protein disulfide isomerase activity; receptor activity; vascular endothelial growth factor receptor 2 binding; vascular endothelial growth factor receptor 2 binding;
Gene ID
3690
Synonyms
ITGB3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); GP3A; integrin beta-3; CD61; GPIIIa; platelet glycoprotein IIIa; platelet membrane glycoprotein IIIa; GT; BDPLT2;
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