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Anti-ITGB3 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGB3 Antibody MOM-18109 1mg Please Inquiry
Product Detail
Cat
MOM-18109
Product Overview
Recombinant Humanized (from mouse) Antibody binds selectively to Human Integrin lpha 2b beta 3, expressed in Chinese Hamster Ovary cells(CHO)
Target
Integrin lpha 2b beta 3
Type
Humanized (from mouse) Fab - G1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, WB and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H chain: QVQLVQS; L Chain: DIQMTQT
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Antigen Description
The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
Function
cell adhesion molecule binding; identical protein binding; integrin binding; platelet-derived growth factor receptor binding; protein binding; protein disulfide isomerase activity; receptor activity; vascular endothelial growth factor receptor 2 binding; vascular endothelial growth factor receptor 2 binding;
Gene ID
3690
Synonyms
ITGB3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); GP3A; integrin beta-3; CD61; GPIIIa; platelet glycoprotein IIIa; platelet membrane glycoprotein IIIa; GT; BDPLT2;
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