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Anti-KDR Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human KDR Antibody Fab Fragment MOM-18202-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18202-F(P)
Product Overview
Recombinant Humanized (from mouse) Antibody Fab Fragment binds selectively to Human VEGF Receptor 2, expressed in E. coli
Target
VEGF Receptor 2
Type
Fab Fragment based on Humanized (from mouse) di - Fab'
Immunogen
Recombinant human soluble extracellular KDR (110 kDa) native protein.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H chain: EVQLVES; L Chain: DIQMTQS
Purity
>95.0% as determined by analysis by RP-HPLC.
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Antigen Description
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi"s sarcoma lesions.
Function
ATP binding; Hsp90 protein binding; growth factor binding; integrin binding; nucleotide binding; protein binding; protein tyrosine kinase activity; receptor activity; receptor signaling protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor-activated receptor activity;
Gene ID
3791
Synonyms
KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor;
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