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Recombinant Anti-MDM4 Single Domain Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human MDM4 Single Domain Antibody NAB-L120 1mg Please Inquiry
Product Detail
Cat
NAB-L120
Product Overview
Single Domain Antibody to human MDM4.
Target
MDM4
Type
llama Single Domain Antibody
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E.coli
Specificity
Tested positive against native human antigen.
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
Protein Mdm4 is a protein that in humans is encoded by the MDM4 gene. The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2.
Function
enzyme binding; metal ion binding; protein binding; zinc ion binding; zinc ion binding;
Gene ID
4194
Synonyms
MDM4; Mdm4 p53 binding protein homolog (mouse); Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse) , mouse double minute 4, human homolog of; p53 binding protein; protein Mdm4; MDMX; protein Mdmx; MDM4-related protein 1; mdm2-like p53-binding protein; double minute 4, human homolog of; p53-binding protein; Mdm4, transformed 3T3 cell double minute 4, p53 binding protein; HDMX; MRP1; MGC132766; DKFZp781B1423;
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