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Anti-MUC5AC Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human MUC5AC Antibody Fab Fragment MOM-18200-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18200-F(E)
Product Overview
Recombinant Chimeric (mouse/human) Antibody Fab Fragment is directed against Human 5AC, expressed in Chinese Hamster Ovary cells(CHO)
Target
5AC
Type
Fab Fragment based on Chimeric (mouse/human) IgG1 - kappa
Immunogen
M1 mucin preparation from the fluid of an ovarian mucinous cyst.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H chain: QVQLKES; L Chain: QVVLTQS
Purity
Purity >95% by SDS-PAGE.
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Antigen Description
Mucins are high molecular weight glycoproteins with 80% carbohydrates and 20% core protein. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.
Function
extracellular matrix structural constituent;
Gene ID
4586
Synonyms
MUC5AC; mucin 5AC, oligomeric mucus/gel-forming; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin-5AC; MUC5; gastric mucin; tracheobronchial mucin; major airway glycoprotein; lewis B blood group antigen; mucin-5 subtype AC, tracheobronchial; mucin 5AC, oligomeric mucus/gel-forming pseudogene; TBM; leB;
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