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Anti-PDGFRA Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human PDGFRA Antibody MOM-18192 1mg Please Inquiry
Product Detail
Cat
MOM-18192
Product Overview
Recombinant Human Antibody is against Human PDGF-R alpha, expressed in Chinese Hamster Ovary cells(CHO)
Target
PDGF-R alpha
Type
Human IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1-kappa, anti-[Homo sapiens PDGFRA (plateletderivedgrowth factor receptor alpha subunit, CD140a, PDGFR2)],Homo sapiens monoclonal antibody
Predicted N terminal
H chain: QLQLQES; L Chain: EIVLTQS
Purity
Purity >95% by SDS-PAGE.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
Receptor that binds specifically to PDGFB and PDGFD and has a tyrosine-protein kinase activity. Phosphorylates Tyr residues at the C-terminus of PTPN11 creating a binding site for the SH2 domain of GRB2.
Function
ATP binding; nucleotide binding; phosphatidylinositol 3-kinase binding; platelet-derived growth factor alpha-receptor activity; platelet-derived growth factor alpha-receptor activity; platelet-derived growth factor binding; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; protein homodimerization activity; protein tyrosine kinase activity; receptor activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor binding; vascular endothelial growth factor-activated receptor activity;
Gene ID
5156
Synonyms
PDGFRA; platelet-derived growth factor receptor, alpha polypeptide; platelet-derived growth factor receptor alpha; CD140a; PDGFR2; PDGFR-alpha; PDGF-R-alpha; CD140a antigen; PDGFRA/BCR fusion; CD140 antigen-like family member A; platelet-derived growth factor receptor 2; alpha-type platelet-derived growth factor receptor; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; CD140A; PDGFR-2; RHEPDGFRA; MGC74795;
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