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Recombinant Anti-PRNP Single Domain Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human PRNP Single Domain Antibody NAB-L125 1mg Please Inquiry
Product Detail
Cat
NAB-L125
Product Overview
Single Domain Antibody to human PRNP.
Target
PRNP
Type
llama Single Domain Antibody
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E.coli
Specificity
Tested positive against native human antigen.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
Function
ATP-dependent protein binding; chaperone binding; copper ion binding; copper ion binding; identical protein binding; metal ion binding; microtubule binding; protein binding; tubulin binding;
Gene ID
5621
Synonyms
PRNP; prion protein; CJD, GSS, prion protein (p27 30) , PRIP; major prion protein; CD230; Creutzfeldt Jakob disease; fatal familial insomnia; Gerstmann Strausler Scheinker syndrome; p27 30; PRP; CD230 antigen; prion-related protein; CJD; GSS; PrP; ASCR; PRIP; PrPc; p27-30; PrP27-30; PrP33-35C; MGC26679;
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