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Anti-RANKL Single Domain Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human RANKL Single Domain Antibody MOM-18712 1mg Please Inquiry
Product Detail
Cat
MOM-18712
Target
RANKL
Type
llama VHH
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E.coli
Specificity
Tested positive against native human antigen.
Storage
At -20°C for one year.
Background
Antigen Description
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
Function
Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL6-mediated signaling events, organism-specific biosystem; Osteoblast Signaling, organism-specific biosystem; Osteoclast Signaling, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem.
Gene ID
8600
Synonyms
TNFSF11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand superfamily member 11; CD254; ODF; OPGL; RANKL; TRANCE; osteoprotegerin ligand; osteoclast differentiation factor; TNF-related activation-induced cytokine; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; sOdf; OPTB2; hRANKL2
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