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Anti-TNF Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TNF Antibody Fab Fragment MOM-18254-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18254-F(E)
Product Overview
Recombinant Human Antibody Fab Fragment specifically binds to Human TNF, expressed in Chinese Hamster Ovary cells(CHO)
Target
TNF
Type
Fab Fragment based on Human [V-kappa]2 - Fc
Immunogen
Full length native protein (purified) (Human).
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H chain: DIQMTQS
Purity
>95.0% as determined by analysis by RP-HPLC.
Storage
At -20°C for one year.
Background
Antigen Description
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
Function
cytokine activity; identical protein binding; protease binding; protein binding; transcription regulatory region DNA binding; tumor necrosis factor receptor binding;
Gene ID
7124
Synonyms
TNF; tumor necrosis factor; TNFA, tumor necrosis factor (TNF superfamily, member 2); DIF; TNF superfamily; member 2; TNF alpha; TNFSF2; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; TNF superfamily, member 2; tumor necrosis factor alpha; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2; TNFA; TNF-alpha;
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