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Anti-TNFRSF10B Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TNFRSF10B Antibody MOM-18180 1mg Please Inquiry
Product Detail
Cat
MOM-18180
Product Overview
Recombinant Human Antibody is specific to Human DR5, expressed in Chinese Hamster Ovary cells(CHO)
Target
DR5
Type
Human IgG1 - lambda
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut, ELISA and most other immunological methods.
Protein Construction
Immunoglobulin G1-lambda, anti-[Homo sapiens TNFRSF10B (tumor necrosis factor receptor superfamily member 10B, DR5, death receptor 5, TRAIL-R2, TNF-related apoptosis-inducing ligand receptor 2, TR-2, CD262)], Homo sapiens monoclonal antibody
Predicted N terminal
H chain: EVQLVQS; L Chain: SELTQDP
Purity
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Function
TRAIL binding; protein binding; receptor activity;
Gene ID
8795
Synonyms
TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor superfamily member 10B; CD262; DR5; KILLER; TRAIL R2; TRICK2A; TRICKB; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer); TRICK2; ZTNFR9; TRAILR2; TRICK2B; TRAIL-R2; KILLER/DR5;
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