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Anti-TNFRSF9 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TNFRSF9 Antibody Fab Fragment MOM-18179-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18179-F(E)
Product Overview
Recombinant Human Antibody Fab Fragment is bind to Human 4-1BB, expressed in Chinese Hamster Ovary cells(CHO)
Target
4-1BB
Type
Fab Fragment based on Human IgG4 - kappa
Immunogen
Ectodomain of human 4-1BB recombinant protein.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Predicted N terminal
H chain: QVQLQQW; L Chain: EIVLTQS
Purity
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
At -20°C for one year.
Background
Antigen Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Function
binding; receptor activity;
Gene ID
3604
Synonyms
TNFRSF9; tumor necrosis factor receptor superfamily, member 9; ILA; tumor necrosis factor receptor superfamily member 9; 4 1BB; CD137; CD137 antigen; T cell antigen ILA; T-cell antigen ILA; 4-1BB ligand receptor; homolog of mouse 4-1BB; receptor protein 4-1BB; T-cell antigen 4-1BB homolog; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; 4-1BB; CDw137; MGC2172; FLJ43501;
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