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Anti-TNFSF12 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TNFSF12 Antibody MOM-18178 1mg Please Inquiry
Product Detail
Cat
MOM-18178
Product Overview
Recombinant Humanized (from mouse) Antibody binds selectively to Human TWEAK receptor, expressed in Chinese Hamster Ovary cells(CHO)
Target
TWEAK receptor
Type
Humanized (from mouse) IgG1 - kappa
Immunogen
Human Fn14 transfected P815.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, ELISA and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1-lambda, anti-[Homo sapiens TNFRSF10B (tumor necrosis factor receptor superfamily member 10B, DR5, death receptor 5, TRAIL-R2, TNF-related apoptosis-inducing ligand receptor 2, TR-2, CD262)], Homo sapiens monoclonal antibody
Predicted N terminal
H chain: EVQLVES; L Chain: DIQMTQS
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Function
cytokine activity; cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding;
Gene ID
8742
Synonyms
TNFSF12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand superfamily member 12; APO3L; DR3LG; TWEAK; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis; MGC20669; MGC129581;
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