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Anti-TPBG Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TPBG Antibody Fab Fragment MOM-18118-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18118-F(P)
Product Overview
Recombinant Mouse Antibody Fab Fragment is bind to Human 5T4, expressed in E. coli
Target
5T4
Type
Fab Fragment based on Mouse Fab - G1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin fragment, anti-[trophoblast glycoprotein (TPBG,5T4)] monoclonal 5T4 gamma1 heavy chain fragment fusion protein[Mus musculus VH (5T4V14: H41>P, S44>G, I69>T, V113>G)-IGHG1_CH1)] - [Glycyl-Glycyl-Prolyl] - superantigen SEA/E-120(synthetic), n
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
5T4 is a 72 kDa transmembrane glycoprotein that exhibits restricted expression in human and mouse adult tissues, is upregulated on many carcinomas and tumour expression correlates with poorer clinical outcome in ovarian, gastric and colorectal cancers. mES cells lack cell surface expression of the 5T4 antigen, and both protein and mRNA are rapidly upregulated following induction of differentiation. This proteins expression correlates with downregulation of OCT-4 and Tra-1–60.
Gene ID
7162
Synonyms
TPBG; trophoblast glycoprotein; 5T4; 5T4 AG; 5T4 oncofetal antigen; 5T4 oncotrophoblast glycoprotein; 5T4 oncofetal trophoblast glycoprotein; M6P1; 5T4AG;
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