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Anti-VEGFA Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human VEGFA Antibody MOM-18011 1mg Please Inquiry
Product Detail
Cat
MOM-18011
Product Overview
Recombinant Humanized (from mouse) Antibody specifically binds to Human VEGF, expressed in Chinese Hamster Ovary cells(CHO)
Target
VEGF
Type
Humanized (from mouse) IgG1 - kappa
Immunogen
Purified intact human VEGF.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
Specificity
Tested positive against native antigen.
Protein Construction
Immunoglobulin G1, anti-(human vascular endothelial growth factor) (human-mouse monoclonal rhumab-VEGF gamma1-chain), disulfide with human-mouse monoclonal rhumab-VEGF light chain, dimer
Predicted N terminal
H chain: EVQLVES; L Chain: DIQMTQS
Purity
Purity >95% by SDS-PAGE.
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. This gene is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized.
Function
cell surface binding; chemoattractant activity; cytokine activity; cytokine activity; extracellular matrix binding; fibronectin binding; growth factor activity; growth factor activity; heparin binding; heparin binding; platelet-derived growth factor receptor binding; protein binding; protein heterodimerization activity; protein homodimerization activity; receptor agonist activity; vascular endothelial growth factor receptor 1 binding; vascular endothelial growth factor receptor 2 binding; vascular endothelial growth factor receptor binding;
Gene ID
7422
Synonyms
VEGFA; vascular endothelial growth factor A; vascular endothelial growth factor , VEGF; VEGF A; VPF; vascular permeability factor; VEGF; MVCD1; MGC70609;
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