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Anti-VEGFA Single Domain Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human VEGFA Single Domain Antibody MOM-0001H 1mg Please Inquiry
Product Detail
Cat
MOM-0001H
Target
VEGFA
Type
llama VHH
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E.coli
Specificity
Tested positive against native human antigen.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
Function
cell surface binding; cytokine activity; extracellular matrix binding; fibronectin binding; growth factor activity; heparin binding; platelet-derived growth factor receptor binding; protein homodimerization activity; vascular endothelial growth factor receptor 1 binding; vascular endothelial growth factor receptor 2 binding.
Gene ID
7422
Synonyms
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; VEGF-A; MGC70609; vascular permeability factor; vascular endothelial growth factor isoform VEGF165
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