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Anti-alk Antibody Fab (CAT#: MOM-18269-F(P))

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DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human alk Antibody Fab Fragment MOM-18269-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment is against Human ALK, expressed in E. coli
  • Target
  • ALK
  • Type
  • Fab
  • Immunogen
  • Prokaryotic recombinant protein corresponding to a region which spans the tyrosine kinase catalytic domain and part of the C-terminus of NPM-ALK transcript (419-520 aa).
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Orphan receptor with a tyrosine-protein kinase activity. Appears to play an important role in the normal development and function of the nervous system. Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif.
  • Function
  • ATP binding; NF-kappaB-inducing kinase activity; nucleotide binding; receptor activity; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity;
  • Synonyms
  • ALK; anaplastic lymphoma receptor tyrosine kinase; anaplastic lymphoma kinase (Ki 1); ALK tyrosine kinase receptor; CD246; CD246 antigen; mutant anaplastic lymphoma kinase; NBLST3

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