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Anti-angpt2 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human angpt2 Antibody Fab Fragment MOM-18529-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18529-F(P)
Product Overview
Recombinant Mouse Antibody Fab Fragment is specific to Human ANGPT2, expressed in E. coli
Target
ANGPT2
Type
Fab
Immunogen
Recombinant purified full length protein (Human).
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by analysis by SDS-PAGE.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Function
metal ion binding; protein binding; receptor binding; receptor tyrosine kinase binding;
Gene ID
285
Synonyms
ANGPT2; angiopoietin 2; angiopoietin-2; Ang2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a; ANG2; AGPT2;
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