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Anti-bace1 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human bace1 Antibody Fab Fragment MOM-18502-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18502-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment specifically binds to Human BACE1, expressed in Chinese Hamster Ovary cells(CHO)
Target
BACE1
Type
Fab
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Function
aspartic-type endopeptidase activity; beta-aspartyl-peptidase activity; enzyme binding; peptidase activity;
Gene ID
23621
Synonyms
BACE1; beta-site APP-cleaving enzyme 1; BACE, beta site APP cleaving enzyme; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; ASP2; BACE; HSPC104; FLJ90568; KIAA1149
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