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Anti-bace1 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human bace1 Antibody MOM-18287 1mg Please Inquiry
Product Detail
Cat
MOM-18287
Product Overview
Recombinant Mouse Antibody is against Human BACE1, expressed in Chinese Hamster Ovary cells(CHO)
Target
BACE1
Type
IgG
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, WB and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Function
aspartic-type endopeptidase activity; beta-aspartyl-peptidase activity; enzyme binding; peptidase activity;
Gene ID
23621
Synonyms
BACE1; beta-site APP-cleaving enzyme 1; BACE, beta site APP cleaving enzyme; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; ASP2; BACE; HSPC104; FLJ90568; KIAA1149
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