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Anti-cd276 Antibody scFv

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human cd276 Antibody scFv Fragment MOM-18535-S(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18535-S(P)
Product Overview
Recombinant Mouse Antibody scFv Fragment is directed against Human CD276, expressed in E. coli
Target
CD276
Type
scFv
Immunogen
Recombinant fragment corresponding to the extracellular domain of Human CD276
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
Purity >95% by SDS-PAGE.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Function
protein binding; receptor binding;
Gene ID
80381
Synonyms
CD276; CD276 molecule; CD276 antigen; B7 H3; B7H3; B7RP 2; B7 homolog 3; costimulatory molecule; B7-H3; B7RP-2; 4Ig-B7-H3;
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