Follow us on:
Dedication / Services
To provide 50000 services and products to global scientific research units every year

Anti-cspg4 Antibody scFv

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human cspg4 Antibody scFv Fragment MOM-18311-S(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18311-S(P)
Product Overview
Recombinant Mouse Antibody scFv Fragment specifically binds to Human CSPG4, expressed in E. coli
Target
CSPG4
Type
scFv
Immunogen
Cell membrane preparation from Human malignant melanoma SK-MEL-28.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.
Function
collagen binding; protein kinase binding; signal transducer activity;
Gene ID
1464
Synonyms
CSPG4; chondroitin sulfate proteoglycan 4; chondroitin sulfate proteoglycan 4 (melanoma associated); HMW MAA; MCSP; MCSPG; MEL CSPG; melanoma associated chondroitin sulfate proteoglycan; MSK16; NG2; chondroitin sulfate proteoglycan NG2; melanoma chondroitin sulfate proteoglycan; melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4 (melanoma-associated); HMW-MAA; MEL-CSPG
Download Datasheet:

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
Loading...
Contact Us

USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email: 

Europe
Tel: 44-207-097-1828


© 2007 - 2017 Creative-Biolabs All Rights Reserved