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Anti-cxcr2 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human cxcr2 Antibody Fab Fragment MOM-18336-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18336-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment specifically binds to Human CXCR2, expressed in Chinese Hamster Ovary cells(CHO)
Target
CXCR2
Type
Fab
Immunogen
Synthetic peptide: MEDFNMESDS FEDFWKGED, corresponding to N terminal amino acids 1-19 of Human CXCR2MEDFNMESDSFEDFWKGED
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Function
C-X-C chemokine receptor activity; G-protein coupled receptor activity; interleukin-8 binding; interleukin-8 receptor activity; receptor activity; signal transducer activity;
Gene ID
3579
Synonyms
CXCR2; chemokine (C-X-C motif) receptor 2; IL8RB, interleukin 8 receptor, beta; C-X-C chemokine receptor type 2; CD182; CMKAR2; CXC-R2; CXCR-2; IL-8R B; GRO/MGSA receptor; IL-8 receptor type 2; interleukin 8 receptor B; chemokine (CXC) receptor 2; interleukin 8 receptor, beta; interleukin 8 receptor type 2; interleukin-8 receptor type B; CXCR2 gene for IL8 receptor type B; high affinity interleukin-8 receptor B; IL8R2; IL8RA; IL8RB; CDw128b
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