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Anti-edar Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human edar Antibody Fab Fragment MOM-18347-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18347-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment is bind to Human EDAR, expressed in Chinese Hamster Ovary cells(CHO)
Target
EDAR
Type
Fab
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
At -20°C for one year.
Background
Antigen Description
EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.
Function
protein binding; receptor activity; transmembrane signaling receptor activity;
Gene ID
10913
Synonyms
EDAR; ectodysplasin A receptor; DL, ectodysplasin 1, anhidrotic receptor , ED3; tumor necrosis factor receptor superfamily member EDAR; ED1R; ED5; EDA1R; EDA3; Edar; EDA-A1 receptor; downless homolog; ectodysplasin-A receptor; downless, mouse, homolog of; ectodermal dysplasia receptor; anhidrotic ectodysplasin receptor 1; ectodysplasin 1, anhidrotic receptor; DL; ED3; HRM1; EDA-A1R; FLJ94390
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