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Anti-epha2 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human epha2 Antibody Fab Fragment MOM-18552-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18552-F(P)
Product Overview
Recombinant Mouse Antibody Fab Fragment is against Human EPHA2, expressed in E. coli
Target
EPHA2
Type
Fab
Immunogen
Recombinant mouse EphA2 extracellular domain
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
Purity >95% by SDS-PAGE.
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Antigen Description
Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). Induces apoptosis in a p53/TP53-independent, caspase-8-dependent manner.
Function
ATP binding; ephrin receptor activity; nucleotide binding; protein binding; receptor activity; transmembrane receptor protein tyrosine kinase activity;
Gene ID
1969
Synonyms
EPHA2; EPH receptor A2; ECK, EphA2; ephrin type-A receptor 2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; epithelial cell receptor protein tyrosine kinase; ECK; CTPA; ARCC2; CTPP1;
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