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Anti-ephb2 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ephb2 Antibody MOM-18352 1mg Please Inquiry
Product Detail
Cat
MOM-18352
Product Overview
Recombinant Mouse Antibody binds selectively to Human EPHB2, expressed in Chinese Hamster Ovary cells(CHO)
Target
EPHB2
Type
IgG
Immunogen
Recombinant His-taggedged fragment corresponding to amino acids 17-200 of Human Eph receptor B2AAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTI RTYQVCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRD CSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWV KVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSG
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, FuncS, IF, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
Receptor for members of the ephrin-B family. Phosphorylates ARHGEF15, leading to its ubiquitination and degradation by the proteasome which promotes EFNB1-dependent synapse formation. Can function in aspects of retinal ganglion cell axon guidance to the optic disk even when lacking its tyrosine kinase domain. Acts as a tumor suppressor.
Function
ATP binding; ephrin receptor activity; nucleotide binding; protein tyrosine kinase activity; receptor activity; transmembrane-ephrin receptor activity; transmembrane-ephrin receptor activity;
Gene ID
2048
Synonyms
EPHB2; EPH receptor B2; DRT, EphB2 , EPHT3, ERK; ephrin type-B receptor 2; Hek5; Tyro5; EPH-like kinase 5; eph tyrosine kinase 3; elk-related tyrosine kinase; protein-tyrosine kinase HEK5; tyrosine-protein kinase TYRO5; renal carcinoma antigen NY-REN-47; tyrosine-protein kinase receptor EPH-3; developmentally-regulated Eph-related tyrosine kinase; DRT; EK5; ERK; CAPB; PCBC; EPHT3; MGC87492
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