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Anti-epor Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human epor Antibody Fab Fragment MOM-18355-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18355-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment is directed against Human EPOR, expressed in Chinese Hamster Ovary cells(CHO)
Target
EPOR
Type
Fab
Immunogen
Human recombinant EPO Receptor (extracellular domain)
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
Purity >95% by SDS-PAGE.
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Antigen Description
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
Function
erythropoietin receptor activity; identical protein binding; protein binding; receptor activity;
Gene ID
2057
Synonyms
EPOR; erythropoietin receptor; EPO-R; MGC138358
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