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Anti-fcrl1 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human fcrl1 Antibody Fab Fragment MOM-18419-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18419-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment is bind to Human FCRL1, expressed in Chinese Hamster Ovary cells(CHO)
Target
FCRL1
Type
Fab
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by analysis by RP-HPLC.
Storage
At -20°C for one year.
Background
Antigen Description
FCRL1 (Fc receptor-like 1) is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 belongs to a new family of immunoglobulin domain-containing receptors known as the Fc receptor-like (FCRL) family. Five closely linked FCRL genes are located near the known FcR genes on chromosome 1q21. They encode 3-9 Ig-like extracellular domains, a transmembrane region, and cytoplasmic domains containing consensus immunoreceptor tyrosine-based activating motifs (ITAM) and/or inhibitory (ITIM) motifs. Although the FCRL members have significant sequence similarity to the Fc receptors, the ligands for these molecules remain unknown. FCRL1 may function as an activating coreceptor in B cells and in B cells activation and differentiation.
Function
receptor activity;
Gene ID
115350
Synonyms
FCRL1; Fc receptor-like 1; Fc receptor-like protein 1; CD307a; FCRH1; IFGP1; IRTA5; hIFGP1; fcR-like protein 1; IFGP family protein 1; fc receptor homolog 1; immunoglobulin superfamily Fc receptor, gp42; immune receptor translocation-associated protein 5; DKFZp667O1421
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