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Anti-fn1 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human fn1 Antibody Fab Fragment MOM-18563-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18563-F(P)
Product Overview
Recombinant Mouse Antibody Fab Fragment binds selectively to Human FN1, expressed in E. coli
Target
FN1
Type
Fab
Immunogen
A region in the ED-A domain of human cellular fibronectin.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
Function
collagen binding; extracellular matrix structural constituent; heparin binding; protein binding;
Gene ID
2335
Synonyms
FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; cold-insoluble globulin; migration-stimulating factor; FN; FNZ; ED-B; GFND; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149;
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