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Anti-gp6 Antibody Fab (CAT#: MOM-18373-F(P))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human gp6 Antibody Fab Fragment MOM-18373-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment is against Human GP6, expressed in E. coli
  • Target
  • GP6
  • Type
  • Fab
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

BACKGROUND

  • Antigen Description
  • Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets. GPVI plays an important role in platelet procoagulant activity which may contribute to arterial and venous thrombus formation. GPVI is expressed in megakaryocytes and platelets. Patients deficient in GPVI suffer from mild hemorrhagic diathesis and their platelets fail to aggregate in response to collagen. There are three isoforms.
  • Function
  • collagen binding; protein binding; receptor activity; transmembrane signaling receptor activity;
  • Synonyms
  • GP6; glycoprotein VI (platelet); platelet glycoprotein VI; GPVI; glycoprotein 6; platelet collagen receptor; GPIV; BDPLT11; MGC138168

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